Endocrine Abstracts

Triple negative breast cancer (TNBC) represents 10–20% of all breast cancers diagnosed, affects young people and is highly aggressive. These tumours lack expression of the receptors that bind estrogen and progesterone and stratify patients for hormonal therapy. The only current therapeutic option for TNBC is chemotherapy which has limited efficacy, and therefore novel therapies are desperately needed. The receptors for estrogen and progesterone belong to the nuclear recep...